Delta-8-THC Promises to Get You High Without the Paranoia or Anxiety | Discover Magazine

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Delta-9-THC is the main drug that causes people's upsurge in the cannabis plant, and it can also be an effective drug. it can

It also stimulates the appetite, which is especially helpful for people living with HIV or undergoing chemotherapy. Synthetic version of THC, called

Since the 1980s, it has been used to treat these diseases, although some people prefer THC to come from the plant itself.

However, although marijuana is a relatively mild drug with minimal side effects (at least compared to alcohol or tobacco), Delta-9-THC has too many shortcomings. Sometimes it causes delusions and anxiety, or

Dizziness and headache. It’s worth noting that most marijuana sold legally in the United States contains

This is why many cannabis consumers switch to the obscure analog of Delta-9-THC called Delta-8-THC. The difference between Delta-8 and Delta-9 is very subtle: both will catch you by surprise, but the former is about


. Many people claim that Delta-8 is a smoother and less anxious mental activity experience compared to the more familiar Delta-9. It seems to have more medicinal effects than conventional THC, such as better analgesic effects, but these claims have not been weighed in clinical trials.

According to these anecdotal reports, Delta-8 quickly became a fashionable new cannabis product, appearing in products such as vape cartridges, soft drinks, gummies and tinctures. The rise in popularity reflects

Before that, just like CBD, the quality control of products or evidence used to back up anecdotal accounts was still scarce. Regarding the Delta-8 product, there are many the same affirmative statements, although scientists have not yet studied its effects in depth.

A cannabis factory is essentially a factory that produces dozens of compounds called cannabinoids. The two most popular are also the most abundant: Delta-9-THC and CBD. But the plant also produces many other so-called minor cannabinoids, including CBG, CBN, THCV, and of course Delta-8-THC. Most cannabis plants produce very little Delta-8, so to obtain usable quantities, a lot of processing and refining are required. However, Delta-8 is

Better than Delta-9, which may make it a better choice for prescription drugs.

The main difference between Delta-8 and Delta-9 lies in the location of specific bonds between the two atoms that make up each THC molecule. "Delta-8 has a double bond on the 8th carbon atom in the chain, and Delta-9 has a double bond on the 9th carbon atom in the chain," Christian co-founder and COO of cannabis beverage company Wunder Peterson explained. Located in San Francisco. Wunder sells a series of Delta-8-filled products that combine Delta-8, Delta-9 and CBD as alcohol substitutes.

That's it? Does the transition of a single carbon bond really make a difference in experience? Based on the limited science available, the answer seems to be yes.

Peter Grinspoon, a primary care physician at Harvard Medical School who specializes in medical marijuana, said: "I think there is a difference." "People report that [Delta-8] is not so much compared to THC. Cause anxiety, sedation and clear mind."

Grinspoon is a member of the board of directors of the advocacy organization "Cannabis Doctor Supervision", which aims to provide patients with evidence about the pros and cons of medical marijuana. He said that Delta-8 has the potential to change the rules of the game for patients (such as the elderly or children) who seek to "reduce confusion and spaciousness or irritability or the person you want to call it". But he warned that the alleged benefits of cannabis-based drugs should not replace evidence.

"Whenever there is another small cannabinoid that starts to make people breathless, I always worry that marketing requirements and people's pocket needs will exceed actual science," Greenspan said.

Peterson agreed: "This research is not yet certain." However, he did point out that Wunder conducted extensive testing to rule out the placebo effect in its products.

But before the market for Delta-8-THC products can approach the current demand for CBD, entrepreneurs and doctors need to know: Is this even legal?

Delta-8 has complicated and vague legality. There is no doubt that Delta-9 is highly illegal: under US federal law, conventional THC is a Schedule I substance, which means that the government classifies it as dangerous as heroin and LSD. This law passed in 1970 enabled

Expensive and difficult-this is part of the reason why we don't know much about Delta-8.


The use of Delta-8 was banned until the United States Drug Enforcement Administration (DEA) updated its list of controlled substances in August this year. Much of the confusion stems from the source of Delta-8. If from

, This is absolutely illegal. If it comes from hemp (a form of the same plant and bred at non-toxic THC levels), then it is thanks to the 2018 Farm Bill. Or, therefore, many marijuana companies have assumed.

"The entire industry... is legal because it is derived from cannabis," said Ryan Cassell, co-founder and chief scientist of Crystal Creek Organics, a cannabis company based in Pensacola, Florida. "The law clearly stipulates that all cannabinoids and products derived from cannabis with a Delta-9-THC content of less than 0.3% are legal." However, according to changing and ambiguous laws, some in the industry are concerned about the DEA crackdown on cannabis farms. .

. Since the legalization of marijuana, chaotic regulations have forced the U.S. Department of Agriculture to

In order to resolve some of these changes and their impact on the industry.

Kassel said: "We will see all of this in the next few months." "For now, our company has to take a step back (from production) and wait for the Delta-8 law and Further clarification of legal status."

At the same time, it is not yet clear what the future prospects of Delta-8 will be. Both Cassell and Peterson said that consumers seem absolutely eager to try new, obscure cannabinoids, but can they legally buy cannabis outside of legal recreational cannabis states, or can scientists easily Research on cannabinoids is still gone.

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